Using densities of estimators to compare pharmacokinetic experiments
نویسندگان
چکیده
Different designs of experiments are compared according to the shape, concentration, etc. of the densities of the least-squares estimator (conditional densities, marginal densities). In contrast with D'Argenio (J. Pharmacokinetics Biopharmaceutics 9(16) (1981) 739-756), where marginal densities have been obtained by simulations, we present here a faster procedure based on well-elaborated approximations of the densities. The stress is on the graphical presentation of the results.
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ورودعنوان ژورنال:
- Computers in biology and medicine
دوره 31 3 شماره
صفحات -
تاریخ انتشار 2001